Abstract TP53 gene alteration confers inferior prognosis in refractory/relapse aggressive B-cell non-Hodgkin lymphoma (r/r B-NHL).From September 2016 to September 2020, 257 r/r B-NHL patients were assessed for eligibility for two trials in our center, assessing anti-CD19 and anti-CD22 chimeric antigen receptor (CAR19/22) T-cell cocktail treatment a
ABSTRACT The microbial carbon pump (MCP) provides a mechanistic illustration of transformation of recalcitrant dissolved organic matter (DOM) in the ocean.Here, we explored and demonstrated the key roles of algae-associated microorganisms (mainly heterotrophic bacteria) in the production and transformation of carboxyl-rich alicyclic molecule (CRAM)
A standard digestion method coupled to electrochemical detection for the monitoring of heavy metals in biological samples has been used for the simultaneous analysis of the target analytes.Square wave anodic stripping voltammetry (SWASV) coupled to disposable screen-printed electrodes (SPEs) was employed as a fast and sensitive electroanalytical me
The thiol-containing compound Dithiothreitol (DTT) has been shown to be toxic to cultured cells by inducing the generation of reactive oxygen species that ultimately cause cell death.However, its effects on multicellular organisms and the environment have not been investigated yet in detail.In this work, we tested the toxicity of DTT to the model i
Background: Amphotericin B (AmB) is among the gold standard antifungal agents used for the treatment of the wide range of fungal infections.However, Body Armor / Protection the drug has various side- effects.Transdermal approach for the delivery of drug is one of the accepted and convenient modes of drug delivery.Aim: The current work was designed